What the people actually building AI said today. One page — a 2-min read.
The strongest signal today was a move from AI that predicts to AI that helps decide what to do next, in both biology labs and software tools. Builders also pointed to a growing demand for apps that work across models and let people collaborate with agents inside familiar interfaces.
Lab Compass aims to turn cell models into experiments
Fabian Theis says Lab Compass uses a model of how cells respond to changes to suggest experiments that could move them toward a desired state. His team ran three or four cycles of model predictions and lab experiments, though he says making that loop work remains difficult. “From mapping, we went to prediction, but now we can go to actually steering the next experiment.”
Rauch sees generated interfaces becoming standard for agents
Guillermo Rauch says AI SDK, Chat SDK and json-render can turn an LLM response directly into an interface on platforms such as Slack and Teams. He predicts generated UI will become the dominant way people interact with conversational agents.
Garry Tan says agent skills need continual evaluation
Garry Tan argues that developers should test agent skills against each new model and remove instructions the model no longer needs. He says he dropped his /investigate skill because Opus 5.5 handles that work better without it. He also praised Aside's computer use in a real Chromium browser.
Peter Yang expects demand for apps that span AI models
Peter Yang observes that apps offering models from multiple labs appear to be getting acquired by the labs, while some remaining examples are open source. He thinks users and enterprises still want apps that can work across model providers.
Texts Wrapped analyzes messages and calls locally on a Mac
Nikunj Kothari reintroduced Texts Wrapped, an open source Mac tool that analyzes iMessage, WhatsApp and phone calls. He says it runs entirely locally without AI, with updated visuals, new insights and better accuracy.
Thariq likes creator apps with built-in agent access
Thariq points to Instagram Edits and Roblox Studio adding built-in MCP support. He likes the pattern because agents can handle part of the work while people continue editing in tools they already know.
Zara Zhang argues a personal site is the new résumé
Zara Zhang says a personal website can show someone's work, thinking and taste more clearly than a list of job titles on LinkedIn. Her advice is to use a site to present that work without relying entirely on existing social platforms.
Source data comes from the open-source project follow-builders by zarazhangrui, released under the MIT license. Summaries are generated by an LLM from that project's public feeds, and the summarization prompts are adapted from it. Every item above links to its original source.
Summaries generated automatically. Read the original before relying on any claim.
